Guadalajara is Mexico's cultural heart of Jalisco, birthplace of mariachi and tequila traditions. Explore the historic center, Guadalajara Cathedral, and murals at Hospicio Cabanas, then browse crafts in Tlaquepaque and Tonala. Sample tortas ahogadas and regional cuisine, and catch live music in Plaza de los Mariachis. Day trips to Tequila town and agave fields are essential.

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